David-Huy Nguyen

Position: Clinical Fellow

Email: David.Nguyen [at] ucsf.edu


I have had a longstanding interest in the intersection of engineering and immunology with applications in preventing and combatting infection and modulating the immune response. I completed my PhD in the laboratory of Robert Langer and post-doc in the Langer and Daniel Anderson labs at MIT working on nanoparticle lipid and polymeric materials for delivery of nucleic acids with applications as vaccines and vaccine adjuvants. I then moved to Stanford, continuing to study immunology with David Lewis while pursuing a medical degree. I completed medicine residency training at UCSF and am now a clinical and research fellow in the Division of Infectious Diseases at UCSF. I joined the Marson Lab in summer of 2016 to work on modulating immune responses at the molecular and genetic level. In my [limited] spare time I’m playing soccer, watching movies, or trying to cook.

Reprogramming human T cell function and specificity with non-viral genome targeting
Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, Chen JW, Schickel J, Pellerin L, Carmody D, Alkorta-Aranburu G, del Gaudio D, Matsumoto H, Morell M, Mao Y, Cho M, Quadros RM, Gurumurthy CB, Smith B, Haugwitz M, Hughes SH, Weissman JS, Schumann K, Esensten JH, May AP, Ashworth A, Kupfer GM, Greeley SAW, Bacchetta R, Meffre E, Roncarolo MG, Romberg N, Herold KC, Ribas A, Leonetti MD, Marson A. Nature. 2018 Jul;559(7714):405-409.