Position: Post-doctoral Fellow
email: youjin.lee [at] UCSF.edu
I joined the Marson lab in 2015 as a post-doctoral fellow with the broad interest in T cell function in the context of autoimmunity. I completed my Ph.D training at Harvard in Vijay Kuchroo's lab. I am currently focused on understanding the heterogeneity of regulatory T cells during autoimmune inflammation. In addition to my work, I am also passionate about dogs (especially mine), watching cooking programs (but not actually cooking), and anything having to do with the New York Football Giants (don’t get me started).
A large CRISPR-induced bystander mutation causes immune dysregulation.
Simeonov DR, Brandt AJ, Chan AY, Cortez JT, Li Z, Woo JM, Lee Y, Carvalho CMB, Indart AC, Roth TL, Zou J, May AP, Lupski JR, Anderson MS, Buaas FW, Rokhsar DS, Marson A. Commun Biol. 2019 Feb 18;2:70.
Discovery of stimulation-responsive immune enhancers with CRISPR activation
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A. Nature. 549; 111-115 (2017)